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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC6L
All Species:
32.12
Human Site:
S124
Identified Species:
50.48
UniProt:
Q9Y5N6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5N6
NP_055136.1
252
28107
S124
I
L
K
S
Y
E
S
S
L
P
Q
T
Q
Q
V
Chimpanzee
Pan troglodytes
XP_001161833
252
28124
S124
I
L
K
S
Y
E
S
S
L
P
Q
T
Q
Q
V
Rhesus Macaque
Macaca mulatta
XP_001113625
252
28130
S124
I
L
K
S
Y
E
S
S
L
P
Q
T
Q
Q
V
Dog
Lupus familis
XP_539609
252
27646
S124
I
L
Q
S
Y
K
S
S
L
P
Q
T
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUJ8
262
29170
G124
I
L
Q
S
Y
K
S
G
L
P
E
T
Q
R
A
Rat
Rattus norvegicus
NP_001028862
262
28796
S124
I
L
Q
S
Y
E
S
S
L
P
E
A
Q
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521050
272
30470
S144
I
L
Q
R
Y
E
S
S
L
P
Q
T
Q
Q
V
Chicken
Gallus gallus
XP_414114
301
33273
S157
I
L
Q
R
Y
E
S
S
L
P
E
A
Q
Q
I
Frog
Xenopus laevis
NP_001086912
225
24746
S124
I
L
N
R
Y
E
S
S
L
S
Q
A
Q
Q
E
Zebra Danio
Brachydanio rerio
NP_997836
256
28612
S123
I
L
Q
R
Y
E
T
S
L
P
A
A
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y1B2
257
29221
V124
L
M
T
L
F
K
G
V
A
A
T
E
D
M
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793313
204
22972
K113
R
Q
K
I
K
V
D
K
T
K
L
V
E
M
T
Poplar Tree
Populus trichocarpa
XP_002316713
285
32005
R122
G
L
S
L
Y
K
D
R
F
I
A
S
L
P
A
Maize
Zea mays
NP_001151122
293
32508
R122
G
L
S
L
Y
K
E
R
F
L
A
A
L
P
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVH3
284
31751
R122
V
L
S
S
Y
K
E
R
F
L
A
S
L
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.4
84.1
N.A.
74.4
70.6
N.A.
66.5
48.5
51.5
51.9
N.A.
26.4
N.A.
N.A.
28.5
Protein Similarity:
100
99.2
98.8
90.8
N.A.
85.5
80.1
N.A.
74.6
61.7
65.8
71.4
N.A.
47
N.A.
N.A.
45.6
P-Site Identity:
100
100
100
80
N.A.
60
66.6
N.A.
86.6
66.6
66.6
60
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
86.6
66.6
73.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
27.3
26.6
N.A.
25.3
N.A.
N.A.
Protein Similarity:
47.3
47.4
N.A.
46.4
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
20
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
27
34
0
0
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
14
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
54
14
0
0
0
20
7
7
0
7
% E
% Phe:
0
0
0
0
7
0
0
0
20
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
7
0
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
0
0
27
0
7
40
0
7
0
7
0
0
0
0
0
% K
% Leu:
7
87
0
20
0
0
0
0
67
14
7
0
20
0
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
14
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
60
0
0
0
20
7
% P
% Gln:
0
7
40
0
0
0
0
0
0
0
40
0
67
54
7
% Q
% Arg:
7
0
0
27
0
0
0
20
0
0
0
0
0
14
0
% R
% Ser:
0
0
20
47
0
0
60
60
0
7
0
14
0
0
0
% S
% Thr:
0
0
7
0
0
0
7
0
7
0
7
40
0
0
7
% T
% Val:
7
0
0
0
0
7
0
7
0
0
0
7
0
0
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
87
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _